Cushing's disease is a metabolic disorder that affects the adrenal glands. The most common cause is a tumor on the pituitary gland, which controls the adrenals. When a tumor is present, the pituitary over-stimulates the adrenals, causing them to over-produce the hormone cortisol.
Symptoms of Cushing's disease vary and can mimic other diseases. But there are some symptoms that are very common to Cushing's.
Fat Deposits
The most common symptom is the collection of fat deposits in the torso, upper back, neck and face. This often results in a rounded, or moon-shaped, face and the appearance of a "buffalo hump" on the upper back.
Skin and Hair Symptoms
Women tend to experience excessive hair growth, especially on the face, neck and abdomen. In both genders the skin becomes fragile, bruises easily and tends to take a long time to heal.
Reproductive Symptoms
Women may experience irregular menstrual cycles. Men may experience erectile dysfunction and reduced fertility.
Bone and Muscle Symptoms
Calcium is stored in the bones and also used for muscle contraction. Cushing's disease robs the bones of calcium and prevents proper muscle contraction.
Other Symptoms
Other symptoms include irritability, anxiety, depression, fatigue, high blood sugar and high blood pressure.
Tags: Cushing disease, high blood, most common, muscle contraction, Symptoms Women, upper back