Osteoporosis can be treated by non-pharmacological, pharmacological and hormonal therapy . This topic will review the most recent approach to therapy of osteoporosis in postmenopausal women. Besides proper diet, exercise, cessation of smoking, calcium and vitamin D supplements following are the most recent advances in the management of osteoporosis.
Instructions
1. Take Alendronate (Fosamax) with adequate amounts of calcium and vitamin D. It can be used as 10 mg once daily or 70 mg once weekly. Alendronate must be taken with plain water in the morning and 30 minutes before breakfast. Stay upright for at least 30 minutes to reduce irritation of the food pipe.
2. Take Risedronate at 5 mg once daily or 35 mg once weekly or one 75 mg tablet on 2 consecutive days once a month (total 2 tablets/month). Risedronate must also be taken with plain water in the morning and 30 minutes before the breakfast. Stay upright for at least 30 minutes to reduce irritation of the food pipe.
3. Use Raloxifene or Evista 60 mg orally any time of the day without regard to meals. This is ideal for postmenopausal women with invasive breast cancer who have osteoporosis and in postmenopausal women with high risk for invasive breast cancer
4. Take Boniva 3 mg intravenously every 3 months or Orally 2.5 mg/day or 150 mg once a month. Intravenous routes are preferred in women who experience severe stomach upset with oral medicines as discussed above.
5. Administer Zoledronic acid intravenous infusion (Zometa or Reclast) once yearly. This has the highest compliance rate and may be preferred in patients who have dementia or other psychosocial issues that prevent them from taking medications on a regular basis.
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